Registration Dossier
Registration Dossier
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EC number: 231-511-9 | CAS number: 7601-89-0
Endpoint summary
Administrative data
Description of key information
Additional information
Aquatic toxicity of perchlorate has been extensively reviewed. In the present dossier are presented the main studies available from notifier side. A more in depth analysis is also provided in the attached position paper ("Perchlorate anion_PNEC derivation") which reviewed available literature and which allowed determination of a relevant PNEC freshwater for Perchlorate.
Here is a summary of the results obtained from the key studies concerning the toxicity of Perchlorate to the different aquatic organisms:
· Short-term toxicity to freshwater fish: LC50 (96h) to Danio rerio was found to be >1000 mg/L.
· Long-term toxicity to freshwater fish: NOEC (12 wk) to Danio rerio was found to be 11.48 mg/L.
· Short-term toxicity to aquatic invertebrates: EC50 (48h) value was found to be >100 mg/L for Daphnia magna.
· Long-term toxicity to aquatic invertebrates: NOEC (7d) to Daphnia magna was determined to be 10 mg/L.
· Toxicity to aquatic algae and cyanobacteria: The growth inhibition study of freshwater algae Pseudokirchneriella subcapitata found ErC10 (72h) and ErC50 (72h) > 435.7 mg/L.
· Toxicity to amphibians: the NOEC (geometric mean of the results of 3 laboratories for which iodide concentration data were relevant and reported) for growth and development of Xenopus laevis was calculated to be 215 µg/L.
· Toxicity to microorganisms (sludge inhibition test): EC50 was determined to be > 700 mg/L.
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