Registration Dossier
Registration Dossier
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EC number: 274-533-4 | CAS number: 70285-70-0
Flammability
Administrative data
- Endpoint:
- self-heating substances / mixtures
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 7-11 January 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- UN Manual of Tests and Criteria: Test N.4 (Test method for self-heating substances)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Adenosine 5'-(trihydrogen diphosphate), monopotassium salt
- EC Number:
- 274-533-4
- EC Name:
- Adenosine 5'-(trihydrogen diphosphate), monopotassium salt
- Cas Number:
- 70285-70-0
- Molecular formula:
- C10H14KN5O10P2
- IUPAC Name:
- potassium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
- Reference substance name:
- Water
- EC Number:
- 231-791-2
- EC Name:
- Water
- Cas Number:
- 7732-18-5
- Molecular formula:
- H2O
- IUPAC Name:
- Oxidane
- Reference substance name:
- Sum of impurities from ADP, K (each < 1 %)
- IUPAC Name:
- Sum of impurities from ADP, K (each < 1 %)
- Test material form:
- solid: particulate/powder
- Details on test material:
- Batch No.: 37779100
Storage Conditions: Refrigerator (approx. 2 °C to 8 °C)
Constituent 1
impurity 1
impurity 2
- Specific details on test material used for the study:
- Batch No.: 37779100
Storage Conditions: Refrigerator (approx. 2 °C to 8 °C)
Results and discussion
Self-heating substances / mixtures
- Key result
- Test procedure:
- 100 mm sample cube at 140°C
- Max. temp. reached:
- 140
- Induction time (h):
- 36
- Result:
- negative outcome (no effect observed)
- Remarks:
- The temperature in the centre of the sample using a 100 mm cube sample (weighed mass: 717.22 g) didn’t exceed the oven temperature of 140 °C within 36 h.
Any other information on results incl. tables
Due to the negative result in the 100 mm cube sample at an oven temperature of 140 °C further tests were not necessary.
Applicant's summary and conclusion
- Interpretation of results:
- not classified based on GHS criteria
- Conclusions:
- The test item Adenosine 5'-diphosphate monopotassium salt (dried) (CAS no. 70285-70-0) indicated no self-heating at atmospheric pressure in the 100 mm cube sample at a temperature of 140 °C.
According to the results of the tests on the self-ignition in the Bowes-Cameron-Cage Test
(UN Test N.4) the test item is classified as follows:
UN Transport Regulation: The test item should not be classified as self-heating substance in Class 4, Division 4.2 according to the UN Transport Regulation.
GHS / CLP Regulation (EC) No 1272/2008 Annex I: 2.11: The test item should not be classified as self-heating substance according to GHS or Regulation (EC) No 1272/2008 (CLP-Regulation) Annex I: 2.11, respectively. - Executive summary:
The test item Adenosine 5'-diphosphate monopotassium salt (dried) (CAS no. 70285-70-0) indicated no self-heating at atmospheric pressure in the 100 mm cube sample at a temperature of 140 °C.
According to the results of the tests on the self-ignition in the Bowes-Cameron-Cage Test
(UN Test N.4) the test item is classified as follows:
UN Transport Regulation: The test item should not be classified as self-heating substance in Class 4, Division 4.2 according to the UN Transport Regulation.
GHS / CLP Regulation (EC) No 1272/2008 Annex I: 2.11: The test item should not be classified as self-heating substance according to GHS or Regulation (EC) No 1272/2008 (CLP-Regulation) Annex I: 2.11, respectively.
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