Registration Dossier
Registration Dossier
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EC number: 403-610-9 | CAS number: 122795-41-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of Neoproxen to Rainbow trout (Salmo gairdneri) was assessed under semi-static conditions in a GLP study according to OECD Guideline No. 203. Fish were exposed to test concentrations of 5.6, 10, 18, 32 and 56 mg/L. Verification of test concentrations showed that the test concentrations slightly decreased over a 24-hour period. However nominal test concentrations were still used to calculate the LC50 values as the test concentrations encompassing the 24-96 hour LC50 values remained at approximately 80% of nominal throughout the study. The 96 h LC50 was 24 mg/L with 95% confidence limits of 18 -24 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- 24 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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