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Diss Factsheets

Physical & Chemical properties

Density

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
bulk density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
23/04/2014 to 26/05/2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Deviations:
not specified
GLP compliance:
yes
Type of method:
pycnometer method
Specific details on test material used for the study:
No further details specified in the study report.
Key result
Type:
bulk density
Density:
1.284 other: g/ml
Temp.:
20 °C
Conclusions:
Solid density measurements-DMSO: Mean value 1.284 g/ml
Solid density measurements-Formic acid: Mena value 12.285 g/ml
Executive summary:

Density was determined in duplicate in the test item with the capillary stoppered pyknometer for solids (without expansion chamber) at 20 ± 0.5 C, according to procedure PEBPL/MUNLAB/10 (CIPAC MT 3.2.1, guideline EEC A3) and employing dimethyl sulfoxide (DMSO) and formic acid as solvent. The first substance (DMSO) was slightly yellow coloured, so the test was repeated with formic acid. The results were very similar in both cases.

 

Solid density measurements – DMSO

Repetition

Density (g/ml)

1

2

Mean value ± SD

1.274

1.294

1.284 ± 0.014

Solid density measurements – Formic acid

Repetition

Density (g/ml)

1

2

Mean value ± SD

1.271

1.300

1.285 ± 0.020

 

Description of key information

Key value for chemical safety assessment

Relative density at 20C:
1.284

Additional information

Density was determined in duplicate in the test item with the capillary stoppered pyknometer for solids (without expansion chamber) at 20 ± 0.5 C, employing dimethyl sulfoxide (DMSO) and formic acid as solvent. The first substance (DMSO) was slightly yellow coloured, so the test was repeated with formic acid. The results were very similar in both cases.

 

Solid density measurements – DMSO

Repetition

Density (g/ml)

1

2

Mean value ± SD

1.274

1.294

1.284 ± 0.014

Solid density measurements – Formic acid

Repetition

Density (g/ml)

1

2

Mean value ± SD

1.271

1.300

1.285 ± 0.020