Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
QSAr
GLP compliance:
no

Test material

1
Chemical structure
Reference substance name:
Reaction products of 2,2-dimethylpropane-1,3-diol with 1-chloro-2,3-epoxypropane
EC Number:
701-333-0
Molecular formula:
C11H20O4
IUPAC Name:
Reaction products of 2,2-dimethylpropane-1,3-diol with 1-chloro-2,3-epoxypropane
Details on test material:
It is a UVCB substance.

Test animals

Species:
rat

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 3 594.52 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:

Acute toxicity: oral (mg/kg, rat LD50): 3594.52
Executive summary:

Acute toxicity: oral (mg/kg, rat LD50): 3594.52