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EC number: 241-253-9 | CAS number: 17211-15-3
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24 October 2017 to 20 November 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Guideline study as required by REACH regulation 1907/2006
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- 27 July 1995
- Deviations:
- no
- Remarks:
- No deviations from the guideline were ascertained.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- 30. May 2008
- Deviations:
- no
- Remarks:
- No deviations from the guideline were ascertained.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Name: dermofeel® PA-12
- CAS No.: 17211-15-3 (old CAS mentioned in study: 14306-25-3)
- EC No.: 241-253-9 (old EC mentioned in study: 238-242-6)
- Source and lot/batch No.of test material: 585542
- Appearance: white solid powder
- Production date: May 2016
- Expiration date of the lot/batch: May 2019
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: The test item was stored in the test facility in a closed vessel at room temperature
(16.0 – 21.6°C) protected from light and humidity.
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: The test item was ground and dried at least overnight. Drying was done in a desiccator.
- Preliminary purification step (if any): not applicable
- Final dilution of a dissolved solid, stock liquid or gel: not applicable
- Final preparation of a solid: not applicable
OTHER SPECIFICS:
Homogeneity: homogenous - Key result
- Melting / freezing pt.:
- >= 63.05 - <= 65.91 °C
- Decomposition:
- no
- Conclusions:
- Melting range evaluated by DSC: 63.05 °C to 65.91 °C (336.20 K to 339.06 K)
- Executive summary:
The determination of the melting and boiling point of dermofeel® PA-12 was performed via DSC (differential scanning calorimetry). In all runs two events were detected. The events
are endothermic and the first event is stated as the melting range under these circumstances as:
53.57 ± 0.30 °C (326.72 ± 0.30 K)
Reference
Pre-test for melting range
The capillary tube containing the test item was set into the block at 18.0 °C. The block was heated until melting started. The temperature was noted at which the first signs of melting
of the test item were observed. When the substance was completely melted, the temperature should be noted again. All observations of the Pre-test for melting range are presented
in the following table.
Table Results of the pre-test for melting range
Observations |
Temperature |
The test item stated to melt |
75 °C |
The test item melted to a turbid liquid like gel. Probably decomposition or transition phase |
88 °C |
Much less than test item was observed, the test tem stayed in white-transparent form and sticky |
After cooling down |
Interpretation
In all DSC measurements two endo thermic events were detected. According to the pre-tests the first event can be identified as melting point.
The second event can be identified as boiling point. As the deviation of melting and boiling point from three independent determinations are higher than 0.5 K, a range of melting and boiling point are stated.
Presentation of results
All results of melting point are presented in the following table.
Table Calculated values
Begin of decomposition |
in °C |
in K |
1 Determination |
65.91 |
339.06 |
2 Determination |
64.47 |
337.62 |
3 Determination |
63.05 |
336.20 |
Min |
63.05 |
336.20 |
Max |
65.91 | 339.06 |
Validity
As the deviations between determinations are > 0.5 K, a range of melting point is stated.
Description of key information
Melting range is 63.05 °C to 65.91 °C (336.20 K to 339.06 K) (OECD 102, DSC method).
Key value for chemical safety assessment
Additional information
The melting and boiling point was determined via DSC (differential scanning calorimetry)
In all runs two events were detected. The events are endothermic and the first event is stated as the melting range under these circumstances
as:
63.05 °C to 65.91 °C (336.20 K to 339.06 K)
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