Registration Dossier
Registration Dossier
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EC number: 284-290-6 | CAS number: 84837-04-7 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Lavandula latifolia, Labiatae.
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data is cited in the database as peer reviewed, and recommended in ECHA Guidance on information requirements. Therefore it is considered as reliable, but with restrictions due to lack of details.
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 2.74
- Remarks on result:
- other: pH and temperature not reported
- Remarks:
- experimental data
- Executive summary:
The HSDB database provides, as secondary source, some physico-chemical properties. A partition coefficient of 2.74 is cited for cineole.
- Endpoint:
- partition coefficient
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data is cited in the database as peer reviewed, and recommended in ECHA Guidance on information requirements. Therefore it is considered as reliable, but with restrictions due to lack of details.
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 2.38
- Remarks on result:
- other: pH and temperature not reported
- Remarks:
- experimental data
- Executive summary:
The HSDB database provides, as secondary source, some physico-chemical properties. A partition coefficient of 2.38 is cited for camphor.
- Endpoint:
- partition coefficient
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data is cited in the database as peer reviewed, and recommended in ECHA Guidance on information requirements. Therefore it is considered as reliable, but with restrictions due to lack of details.
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 2.97
- Remarks on result:
- other: PH and temperature not reported
- Remarks:
- experimental data
- Executive summary:
The HSDB database provides, as secondary source, some physico-chemical properties. A partition coefficient of 2.97 is cited for linalool.
- Endpoint:
- partition coefficient
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data is cited in the database as peer reviewed, and recommended in ECHA Guidance on information requirements. Therefore it is considered as reliable, but with restrictions due to lack of details.
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 4.16
- Remarks on result:
- other: experimental
- Executive summary:
The HSDB database provides, as secondary source, some physico-chemical properties. A partition coefficient of 4.16 is cited for beta-pinene.
- Endpoint:
- partition coefficient
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data comes from an online compilation using secondary data sources. There is no experimental study reference, however data is cited in the database as peer reviewed, and recommended in ECHA Guidance on information requirements. Therefore it is considered as reliable, but with restrictions due to lack of details.
- Reason / purpose for cross-reference:
- reference to other study
- Principles of method if other than guideline:
- No data.
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 4.83
- Remarks on result:
- other: experimental
- Executive summary:
The HSDB database provides, as secondary source, some physico-chemical properties. A partition coefficient of 4.83 is cited for alpha-pinene.
Referenceopen allclose all
temperature and pH not specified
Description of key information
Major components of the substance (about 80% of the composition) are ranging between 2.38 and 2.97 (literature) and some minor constituents have a log Kow > 4.
Key value for chemical safety assessment
Additional information
No study was conducted on the oil itself.
The test item is a natural complex substance (NCS). It is a mixture of several constituents, but three of them represent about 80% of that mixture.
Log P of each of these three major constituents were reported below. These data come from literature data :
- linalool log Kow ca 2.97,
- camphor logKow ca 2.38,
- cineol 1,8 logKow ca 2.74.
However, the substance contains minor constituents, such as alpha and beta pinene, with a logKow > 4 according to literature data :
- alpha pinene: logKow ca 4.83
- beta pinene: logKow ca 4.16
As no CSA is required for the tonnage band of concern, no key value was retained.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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