7,8,9,10-Tetrahydro-8-(trifluoroacetyl)-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine

Guidance on Safe Use

First-aid measures

Description of First Aid Measures

Eye Contact: Flush with water while holding eyelids open for at least 15 minutes. Seek medical attention

immediately.

Skin Contact: Remove contaminated clothing. Flush area with large amounts of water. Use soap. Seek

medical attention.

Ingestion: Never give anything by mouth to an unconscious person. Wash out mouth with water. Do not

induce vomiting unless directed by medical personnel. Seek medical attention immediately.

Inhalation: Remove to fresh air and keep patient at rest. Seek medical attention immediately.

Fire-fighting measures

Extinguishing Media: Extinguish fires with CO2, extinguishing powder, foam, or water.

Special Hazards Arising from the Substance or Mixture

Hazardous Combustion

Products:

Formation of toxic gases is possible during heating or fire.

Fire / Explosion Hazards: Very high sensitivity of a dust cloud to ignition, based on minimum ignition energy. Very strong

dust explosion characteristic.

Advice for Fire-Fighters

During all fire fighting activities, wear appropriate protective equipment, including self-contained breathing apparatus.

Accidental release measures

Personal Precautions, Protective Equipment and Emergency Procedures

Personnel involved in clean-up should wear appropriate personal protective equipment (see Section 8). Minimize exposure.

Environmental Precautions

Place waste in an appropriately labeled, sealed container for disposal. Care should be taken to avoid environmental release.

Methods and Material for Containment and Cleaning Up

Measures for Cleaning /

Collecting:

Contain the source of the spill if it is safe to do so. Collect spilled material by a method that

controls dust generation. Avoid use of a filtered vacuum to clean spills of dry solids, due to the

potential for electrostatic discharge and the very strong dust explosion characteristic and high

sensitivity to ignition.

Additional Consideration for

Large Spills:

Non-essential personnel should be evacuated from affected area. Report emergency

situations immediately. Clean up operations should only be undertaken by trained personnel.

Handling and storage

Ground and bond all bulk transfer equipment. Avoid open handling. Minimize dust generation. Use local exhaust ventilation or

perform work under fume hood/fume cupboard. When handling, use appropriate personal protective equipment (see Section 8).

Wash hands and any exposed skin after removal of PPE. All conductive elements of the system that contact the dry substance

should be properly bonded and grounded and equipped with proper explosion relief or suppression systems. This material should

not be flowed through nonconductive ducts or pipes because of the potential for electrostatic discharge ignition. Restricting the

use of high resistivity materials, such as plastics, should be considered. Releases to the environment should be avoided. Review

and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure

or environmental releases. Potential points of process emissions of this material to the atmosphere should be controlled with

dust collectors, HEPA filtration systems or other equivalent controls.

Storage Conditions: Store at room temperature in properly labeled containers. Keep away from heat, sparks and flames

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

Not regulated

Shipping

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

Not regulated

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

Not regulated

Shipping

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

Not regulated

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Engineering Controls: Engineering controls should be used as the primary means to control exposures. Use process

containment, local exhaust ventilation, or other engineering controls to maintain airborne levels

below recommended exposure limits.

Personal Protective

Equipment:

Refer to applicable national standards and regulations in the selection and use of personal

protective equipment (PPE).

Hands: Wear impervious gloves as minimum protection.

Eyes: Wear safety glasses as minimum protection.

Skin: Wear impervious protective clothing when handling this compound.

Respiratory protection: If the applicable Occupational Exposure Limit (OEL) is exceeded, wear an appropriate

respirator with a protection factor sufficient to control exposures to below the OEL.

Stability and reactivity

Reactivity: No data available

Chemical Stability: Stable under normal conditions of use.

Possibility of Hazardous Reactions

Oxidizing Properties: No data available

Conditions to Avoid: Keep away from heat and other sources of ignition, including electrostatic discharge.

Incompatible Materials: As a precautionary measure, keep away from strong oxidizers

Hazardous Decomposition

Products:

No data available

Disposal considerations

Dispose of waste in accordance with all applicable laws and regulations. Member State

specific and Community specific provisions must be considered. Considering the relevant

known environmental and human health hazards of the material, review and implement

appropriate technical and procedural waste water and waste disposal measures to prevent

occupational exposure and environmental release. It is recommended that waste minimization

be practiced. The best available technology should be utilized to prevent environmental

releases. This may include destructive techniques for waste and wastewater.