Registration Dossier
Registration Dossier
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EC number: 216-241-1 | CAS number: 1531-77-7
Endpoint summary
Administrative data
Description of key information
Experimental data on the potential of skin corrosion or irritation of dothiepinone are not available.
QSAR Toolbox has identified one structural alert for skin irritation. Substances with "Ketones" structural alert can cause irritation of the skin as proposed by Hulzebos et al.
In order to estimates skin irritatiion potential from physicochemical property ranges and structural rules, the software Toxtree (v.2.6.13) has been used; prediction is not possible. The substance has been predicted as “Unknown”.
Overall, data are judged as inconclusive for the classification.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no study available
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Available data (i) mechamistic profile (QSAR Toolbox), (ii) Toxtree prediction are judged as inconclusive for the classification.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
