Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 922-147-8 | CAS number: -
Auto flammability
Administrative data
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment. No information on purity of the substance.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.16 (Relative Self-Ignition Temperature for Solids)
- Deviations:
- yes
- Qualifier:
- according to guideline
- Guideline:
- other: VDI Guideline 2263 Part 1: Autoignition-Testing as per Grewer
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- other: ESCIS Expert Commission for Safety in the Swiss Chemical Industry, Booklet 1 ''Sicherheitstests fur Chemikalien''.
- Deviations:
- not specified
- Principles of method if other than guideline:
- Modifications to the EU A.16 Method: A heating rate of 1.0-1.2 deg C/min or 0.6 deg C/min is used instead of 0.5 deg C/min due to an alternative Swiss Chemical Industry method and technical restriction of the apparatus used. Cylindric wire baskets with 0.2 mm openings are used.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- methyl (1R,2R,4S)-2-[(hex-5-en-1-yl)(methyl)carbamoyl]-4-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)cyclopentane-1-carboxylate
- EC Number:
- 922-147-8
- Cas Number:
- 1042695-87-3
- Molecular formula:
- C32H41N3O5S
- IUPAC Name:
- methyl (1R,2R,4S)-2-[(hex-5-en-1-yl)(methyl)carbamoyl]-4-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)cyclopentane-1-carboxylate
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Name of test material (as cited in study reports): JNJ-39125593-AAA (T003019)
- Physical state: solid
- Appearance: white powder
Constituent 1
- Specific details on test material used for the study:
- no data
Results and discussion
Relative self-ignition temperature (solids)
- Remarks on result:
- no self ignition observed under the test conditions
Any other information on results incl. tables
The sample is heated from room temperature (about 20 deg C) to ± 170 deg C (above the melting point).
The sample shows no self-heating to 400 deg C in the test run.
Applicant's summary and conclusion
- Conclusions:
- In conclusion, the tested substance T003019 is not auto-flammable according to the criteria as described in the guideline.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
