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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
22 June 2016 to 14 October 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
European Community (EC), EC no. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.4: “Vapour Pressure", Official Journal of the European Union no. L220, August 24, 2009.
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no.104: "Vapour Pressure", March 23, 2006.
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7950: "Vapor pressure", August 1996.
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: isothermal thermogravimetry
Specific details on test material used for the study:
Batch: RC-1045Study specific test item informationPurity/composition correction factor: No correction factor requiredChemical name (IUPAC), synonym or trade name: Amides, tallow, N,N-bis(2-hydroxypropyl)CAS Number: 1454803-04-3Test item handling: No specific handling conditions required
Key result
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Temp.:
20 °C
Vapour pressure:
0 mm Hg
Key result
Temp.:
25 °C
Vapour pressure:
0 Pa
Key result
Temp.:
25 °C
Vapour pressure:
0 mm Hg

Results of the isothermal TGA analysis

Temperature

[°C]

Weight loss

[μg/min]

νT

[g/cm2/h]

LogνT

Log PT

PT

[Pa]

160

 

 

170

  

180

 

 

190

 

 

5.653

6.733

 

9.241

11.29

 

18.08

20.84

 

36.35

38.49

6.75 x 10-4

8.04 x 10-4

 

1.10 x 10-3

1.34 x 10-3

 

2.16 x 10-3

2.49 x 10-3

 

4.34 x 10-3

4.59 x 10-3

-3.17

-3.09

 

-2.96

-2.87 

-2.67

-2.60

 

-2.36

-2.34

0.93

1.02

 

1.18

1.27

1.51

1.58

 

1.86

1.88

8.6

10

 

15

19 

32

38

 

72

77

 

Vapour pressure of the test item

Temperature

[°C]

Log PT

PT

[Pa]

PT

[mm Hg]

20

 

25

-5.68

 

-5.34

2.1 x 10-6

 

4.6 x 10-6

1.6 x 10-8

 

3.5 c 10-8

 

Conclusions:
The vapour pressure of the test item at 20°C (293K) and 25°C (298K) was:2.1e-6 Pa (1.6e-8 mm Hg) at 20°C4.6e-6 Pa (3.5e-8 mm Hg) at 25°C
Executive summary:

The purpose of the study was to determine the physico-chemical properties for MLA-3202.

 

The vapour pressure of the test item (PT) was determined by the isothermal thermogravimetric effusion method, in accordance with the following guidelines:

European Community (EC), EC no. 761/2009, Part A: Methods for the Determination of Physico-Chemical Properties, Guideline A.4: “Vapour Pressure", Official Journal of the European Union no. L220, August 24, 2009.

Organization for Economic Co-operation and Development (OECD), OECD Guidelines for the Testing of Chemicals no.104: "Vapour Pressure", March 23, 2006.

United States Environmental Protection Agency (EPA), Product Properties Test Guidelines no. OPPTS 830.7950: "Vapor pressure", August 1996.

 

The isothermal TGA effusion method was applied for the determination of the vapour pressure of MLA-3202.

 

The vapour pressure of the test item at 20°C (293K) and 25°C (298K) was:

2.1e-6 Pa (1.6e-8 mm Hg) at 20°C

4.6e-6 Pa (3.5e-8 mm Hg) at 25°C

Description of key information

Key value determined in a GLP accredited laboratory study by the isothermal thermogravimetric effusion method, in accordance with EU Method A.4,OECD Guideline.104and US EPA Procedure OPPTS 830.7950.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

The isothermal TGA effusion method was applied for the determination of the vapour pressure of MLA-3202.

 

The vapour pressure of the test item at 20°C (293K) and 25°C (298K) was:

2.1e-6 Pa (1.6e-8 mm Hg) at 20°C

4.6e-6 Pa (3.5e-8 mm Hg) at 25°C