Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
other: peer reviewed literature information
Adequacy of study:
other information

Data source

Reference
Reference Type:
review article or handbook
Title:
SIDS Initial Assessment Report Isobutanol 78-83-1
Author:
United States of America, U.S. Environmental Protection Agency
Year:
2001
Bibliographic source:
OECD

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EPA OTS 798.1175 (Acute Oral Toxicity)

Test material

Test material form:
liquid

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Results and discussion

Effect levelsopen allclose all
Sex:
male
Dose descriptor:
LD50
Effect level:
> 2 830 mg/kg bw
Sex:
female
Dose descriptor:
LD50
Effect level:
3 350 mg/kg bw

Applicant's summary and conclusion