Salbutamol

Guidance on Safe Use

First-aid measures

Description of the first aid measures:

- Eye contact: wash immediately with large amounts of water or normal saline. Keep eyelids open

with the fingers. Get medical advice if adverse symptoms will appear.

- Skin contact: remove contaminated clothes and shoes immediately. Wash affected area with soap

or mild detergent and large amount of water until no evidence of substance remains

(15-20 minutes). Get medical advice if adverse symptoms will appear.

- Ingestion: if swallowed wash mouth with water provided person is conscious. Treat

symptomatically and supportively. Get medical advice if adverse symptoms will

appear.

- Inhalation: avoid breathing aerosols and dusts that may be generated by handling of the product.

Remove the person from the exposed area to fresh air immediately. Get medical

advice if adverse symptoms will appear.

Most importanti symptoms and effects (acute and delayed):

- Acute effects: harmful if swallowed;

adverse effects may include: drowsiness, dizziness, loss of memory, slurred speech,

clumsiness, anxiety, confusion, weakness, constipation, diarrhea, nausea or

vomiting, abdominal or stomach pain, change in vision, yellow eyes or skin, mental

depression, fast, pounding or irregular heartbeat, change in sexual desire or ability,

watering or dry mouth, increased thirst, false sense of well-being, headache, muscle

spasm, urinary problems and seizures.

- Delayed effects: unknown

Fire-fighting measures

EXTINGUISHING MEDIA:

Suitable extinguishing media: water spray or regular foam, dry powder, CO2.

- Unsuitable extinguishing media: unknown.

SPECIAL HAZARDS ARISING FROM THE SUBSTANCE

- Hazardous combustion products: thermal decomposition or combustion may generate toxic and hazardous fumes

(COx, NOx).

- Other special hazards: unknown.

ADVICE TO FIREFIGHTERS

Technical actions for protection: keep containers cool with water.

- Special protective equipment for

firefighters: wear boots, overalls, gloves, eye and face protection and breathing apparatus.

Equipment must be conformed with EN criteria and used in highest condition of protection on the basis of the information reported in the previous sub-sections

Accidental release measures

Wear appropriate protective equipment to prevent contamination of the skin, eyes and personal clothing.

In case of fire and/or and explosions avoid breathing fumes and vapors. Use a self-contained breathing apparatus (SCBA) and appropriate protective clothing.

Recover the substance for suction or other mechanical means and wash the area with plenty of water and detergents. Store the material into a company that specializes pending disposal. Containers must be cleaned up and disposed of as waste remediation above.

Handling and storage

- Recommandation for handling: handle away from sparkles and flames - sources of ignition;

handle in a well ventilated place;

avoid contact with incompatible materials;

wear suitable Personal Protection Equipment (see section 8);

keep the substance away from drains, surface or ground waters.

- Recommandation for personal hygiene: do note eat, drink and smoke in the working areas;

wash hands after handling the substance;

remove contaminated clothing and protective equipment before entering

eating areas

The substance is not classified for any physical and chemical properties and no risk management is foreseen.

Other advice:

- ventilation requirements: use in a well ventilated place at room temperature, less than 30°C;

- containers: keep containers tightly closed and with correctly labeled;

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

a) Eye and Face protection: safety goggles as for EN 166; facial shield.

b) Skin protection

- hands protection: wear protective gloves.

Gloves resistant to chemical agents as for the EN 374, parts 1, 2 e 3 and the

European Directive 89/89/CEE.

The glove material has to be made of rubber or polyethylene impermeable and

resistant to the substance.

Make the choice of the glove material on consideration of the penetration

times, rates of diffusion and degradation.

The selection of suitable gloves not only depends on the material, but also on

further marks of quality and varies from manufacturer to manufacturer.

- other, body protection: select the suitable protective equipment based on the activity of use and

possible exposure. Wear gauntlets, boots, bodysuit and other devices in

accordance with EN 13982.

c) Respiratory protection: dust mask with approved dust filter.

Use only devices approved by the Competent Authorities such as NIOSH

(USA) and CEN (EU).

In the case of brief exposure or minimal exposure use respiratory filter; in case

of intensive and sustained exposition wear self-contained breathing.

d) Thermal hazards: not foreseen in the standard use. Assess possible Personal Protection

Equipment on the basis of specific uses of the substance.

Stability and reactivity

The substance is stable at the normal condition of temperature and pressure and if stored in closed containers in well

ventilated and cool place.

Under recommended conditions of storage and use, no hazardous reactions occur.

Protected to temperatures exceeding 30°C.

Thermal decomposition or combustion may include toxic and hazardous fumes of COx, NOx.

Disposal considerations

The substance must be incinerated in a suitable incinerator authorized by the Competent Authorities.

Should never be disposed through wastewater.

Refers to Community/National/Local requirements concerning the waste disposal.