Registration Dossier
Registration Dossier
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EC number: 943-483-1 | CAS number: -
Carcinogenicity
Administrative data
Description of key information
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 375 mg/kg bw/day
- Study duration:
- chronic
- Species:
- rat
Carcinogenicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Carcinogenicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Non-neoplastic lesions of the kidney were observed in both dose groups of both sexes of rats and mice.
In addition, an evaluation between the members of ETAD, confirmed that there is no evidence to classify Acid Orange 3 as carcinogenic.
Additional information
Non-neoplastic lesions of the kidney were observed in both dose groups of both sexes of rats and mice.
In addition, an evaluation between the members of ETAD, confirmed that there is no evidence to classify Acid Orange 3 as carcinogenic.
Justification for selection of carcinogenicity via oral route endpoint:
Higher dose
Carcinogenicity: via dermal route (target organ): urogenital: kidneys
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