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EC number: 205-585-8 | CAS number: 143-13-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
The OECD [Q]SAR Toolbox predictions in the absence and presence of S9 -mix are both negative and use the following strains: TA1535, TA1537, TA98, TA100, TA102 and WP2uvrA. The predictions in the absence and presence of S9 -mix both have very high confidence limits.
WOE Ames Test.
In a reverse gene mutation assay in bacteria, performed according to the OECD Guideline 471 and in compliance with GLP, strains of Salmonella typhimurium (TA1535, TA1537, TA98, TA100 and TA102) were exposed to DECYLACETATE at the various concentrations, including a toxic dose level or the maximum recommended dose level. A metabolic activation system used in this test was10 % S9; S9 fraction prepared from liver homogenates of male Sprague-Dawley rats induced with Aroclor 1254 (500 mg/kg bw). Negative, vehicle and positive control groups were also included in mutagenicity tests. In the absence of S9-mix, the test item was bacteriotoxic to strains TA100 and TA102 at 500 μg/plate, to strain TA1537 at 1500 μg/plate, and to strain TA98 at 5000 μg/plate. In the presence of S9-mix the test item was bacteriotoxic to the strains TA1537 and TA102 at 500 μg/plate and to strains TA1535, TA98, and TA100 at 1500 μg/plate. Precipitation of the test item on the plates was not observed. The test item did not induce a significant or dose related increase in the mutation frequency of the tester strains in the absence and presence of a metabolic activation system.The positive and negative/vehicle controls induced the appropriate responses in the corresponding strains indicating the validity of the study.
Under the test conditions, DECYLACETATE was considered as not mutagenic in this bacterial system. Supporting Ames Test.In a reverse gene mutation assay in bacteria, strains ofSalmonella typhimurium (TA 1535, TA 1537, TA 1538, TA 98 and TA 100) were exposed to Decyl acetate at the various concentrations, including dose levels that were toxic. Vehicle and positive control groups were also included in the mutagenicity tests. Decyl acetate proved extremely toxic to the bacteria resulting in either the absence or incomplete formation of the background bacterial lawn at most dose levels. No substantial increase in the revertant colony numbers of any of the five strains were following treatment with Decyl acetate at any dose level, either in the presence or absence of metabolic activation. The positive and vehicle controls induced the appropriate responses in the corresponding strains indicating the validity of the study.
Under the test conditions, Decyl acetate was considered as not mutagenic in this bacterial system.Short description of key information:
Data: The [Q]SAR (Domain - EPA ESTERS) along with the 2 bacterial gene mutation assays, as WOE studies were both on the read-across substance Decyl acetate. The main study is a GLP study regared as K1 for the donor substance but as K2 for the target substance. The second older study is K4 and is also on Decyl acetate but it provides the same result as the key study.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
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