Registration Dossier
Registration Dossier
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EC number: 416-140-4 | CAS number: 145650-60-8
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data obtained through inquiry process; SNIF file obtained from ECHA.
Data source
Reference
- Reference Type:
- other: SNIF
- Title:
- Unnamed
- Year:
- 1 994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Version / remarks:
- (calculation)
- Deviations:
- not specified
- GLP compliance:
- yes
- Type of method:
- other: calculated with the CLOGP program, release 3.42 (for calculating log P oct/water from structure based on a simple but rigorous programmable-method of dissecting a solute structure into chemically-meaningful fragments)
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Body responsible for the test
- IUPAC Name:
- Body responsible for the test
- Test material form:
- not specified
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- >= 12
- Temp.:
- 20 °C
Applicant's summary and conclusion
- Conclusions:
- The partition coefficient (n-octanol/water) of the test substance was determined in a GLP study according to EU method A.8. As the substance does not dissolve in water and the test could not be performed, a calculation was done with the CLOGP program (release 3.42) and the log Pow was determined to be ≥ 12 at 20°C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
