Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-438-8 | CAS number: 140-88-5
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable well documented publication.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Monograph on Fragrance Raw Materials- Ethyl acrylate.
- Author:
- Opdyke DLJ
- Year:
- 1 975
- Bibliographic source:
- Fd. Cosm. Toxicol., Suppl. 13: 801-802
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 974
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- study with volunteers
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Ethyl acrylate
- EC Number:
- 205-438-8
- EC Name:
- Ethyl acrylate
- Cas Number:
- 140-88-5
- Molecular formula:
- C5H8O2
- IUPAC Name:
- ethyl acrylate
- Details on test material:
- - Name of test material (as cited in study report): Ethyl acrylate
- Analytical purity: no data
Constituent 1
Method
- Type of population:
- general
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- Ethyl acrylate produced sensitization reactions in ten of the 24 volunteers. The threshold limit value for ethyl acrylate has been set at 25 ppm (American Conference of Governmental Industrial Hygienists. 1973).
Any other information on results incl. tables
Ethyl acrylate showed a skin sensitizing effect in the maximization test.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
