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EC number: 237-523-0 | CAS number: 13825-74-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Target substance titanium oxide sulphate itself is unstable in water and produces insoluble titanium oxide after rapid hydrolysis. Based on the information available from the key study on the target chemical itself and from two supporting studies on final hydrolysis product TiO2, it can be concluded that neither target compound titanium oxide sulphate nor the final hydrolysis transformation products titanium dioxide and sulphuric acid (after neutralisation) exhibit acute toxic effects to aquatic algae.
Key value for chemical safety assessment
Additional information
Titanium oxide sulphate rapidly hydrolyses in water, resulting in the formation of titanium dioxide and causing an increase in acidity. Titanium dioxide is very poorly soluble in water at neutral pH (< 0.1 μg/L), thus excess titanium dioxide will be present as insoluble matter.
In the study of Egeler (2010) on target chemical titanium oxide sulphate itself, after pH adjustment, and precipitation of TiO2, the measured concentrations of titanium in the liquid phase were below the limit of detection of 0.0027 mg/L in all samples. The results of the study demonstrate that under pH-adjusted conditions the no-observed effect loading rate (NOELR) forPseudokirchneriella subcapitatafor the parameters yield and growth rate is ≥ the water-accommodated fraction (WAF) at a loading rate of 100 mg test item/L (nominal concentration).Therefore it is to be concluded that Egeler in fact analysed the effects of titanium dioxide.
Furthermore the two supporting studies uniformly show the absence of adverse effects on algae at nominal concentrations that are several orders of magnitude higher than the soluble concentration plus additional load of suspended microdisperse matter in excess. Physical effects on the algae caused by TiO2 particles, such as adsorption and shading, might occur, however such effects are not to be attributed to toxic properties of the substance.
Based on the information available from the key study on the target chemical itself and from two supporting studies on final hydrolysis product TiO2, it can be concluded that neither target compound titanium oxide sulphate nor the final hydrolysis transformation products titanium dioxide and sulphuric acid (after neutralisation) exhibit acute toxic effects to aquatic algae.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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