2-ethylhexyl methacrylate

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.003 mg/L

Assessment factor:

50

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.022 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0 mg/L

Assessment factor:

500

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

10 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

2.24 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

0.224 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.446 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

PNEC aqua (freshwater)

Acute toxicity studies were conducted with 2-EHMA in fish, daphnia and algae. Chronic studies with 2-EHMA are available for daphnia and algae. The PNEC aqua (freshwater) was based on the NOEC of 0.174 mg/L (mean value derived from two long term daphnia magna reproduction tests). Among the trophic levels tested, the invertebrate toxicity tests gave the lowest NOEC and the lowest LC50.

An assessment factor of 50 was applied to the NOEC to calculate the PNEC aqua (freshwater) in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008.

PNEC aqua (marine)

No tests with marine species are available. The PNEC aqua (marine water) was based on the NOEC of 0.174 mg/L (mean value derived from two long term daphnia magna reproduction tests). Among the trophic levels tested, the invertebrate toxicity tests gave the lowest NOEC and the lowest LC50. An assessment factor of 500 was applied to the NOEC to calculate the PNEC aqua (marine water) in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008.

PNEC aqua (intermittent releases)

The PNEC aqua (intermittent releases) was based on the lowest acute toxicity value of 2.18 mg/L (mean value derived from two short term daphnia magna studies).

Based on the available data set, an assessment factor of 100 was applied to the lowest EC/LC50 to calculate the PNEC aqua (intermittent releases) in accordance with Guidance on information requirements and chemical safety assessment, Chapter R.10: Characterisation of dose [concentration]-response for environment, 2008.

PNEC STP

In a ready biodegradation test there was no bacterial toxicity (modified MITI (I) test, OECD 301C) up to 100 mg/L, the maximum concentration tested. An AF of 10 is applied to the NOEC, according to table R.10-6 from guidance document.

PNEC sediment (freshwater, marine)

No toxicity data for sediment dwelling organisms are available. Thus, the PNEC for freshwater as well as marine sediment has been calculated with the equilibrium partitioning method using EUSES 2.1.

The following data have been taken into account for the calculation:

Molecular weight [g/mol]	198.3
Melting point [°C]	-50
Boiling point [°C]	227.6
Vapour pressure [hPa], 20°C	6.5
Water solubility [mg/L], 20°C	3.1
Log Kow	4.95
Koc (Kow method) L/kg	6400
PNEC aqua, freshwater [mg/L]	0.00348

PNEC air

A PNEC air was not calculated for 2-EHMA since the substance is rapidly degraded in air. This indicates that there would be only little accumulation of the test substance in the air.

PNEC soil

No toxicity data for soil organisms are available. Thus, the PNEC soil has been calculated with the equilibrium partitioning method using EUSES 2.1.

The following data have been taken into account for the calculation:

Molecular weight [g/mol]	198.3
Melting point [°C]	-50
Boiling point [°C]	227.6
Vapour pressure [hPa], 20°C	6.5
Water solubility [mg/L], 20°C	3.1
Log Kow	4.95
Koc (Kow method) L/kg	6400
PNEC aqua, freshwater [mg/L]	0.00348

   

PNEC oral

A PNEC oral was not calculated for 2-EHMA since the substance is readily biodegradable. Due to the well investigated metabolic pathways the probability of being rapidly metabolised in exposed organisms is high. Together with the reported BCF of 37 this indicates that there would be no significant potential for biomagnification of the test substance in the food chain.

Conclusion on classification

According to the criteria of CLP (1272/2008/EC, and 2nd ATP 286/2011/EC), 2 -Ethylhexyl methacrylate has to be classified as Aquatic environment / Chronic, Category: Chronic 3.

 

According to the criteria of UN-GHS(2009) for acute aquatic hazards, 2-EHMA has to be classified as Aquatic Acute Category 2 and A

quatic environment / Chronic, Category: Chronic 3.