Registration Dossier
Registration Dossier
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EC number: 500-094-8 | CAS number: 37208-53-0 1 - 6.5 moles propoxylated
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 1 988
- Report date:
- 1988
Materials and methods
- Study type:
- poisoning incident
- Endpoint addressed:
- skin irritation / corrosion
- skin sensitisation
Test guideline
- Qualifier:
- no guideline required
- GLP compliance:
- no
Test material
- Details on test material:
- - Name of test material (as cited in study report): D40 (D40 is a product 2,2',2''-Nitrilotriethanol, propoxylated (NLP #15))
-No other information is reported.
Constituent 1
Method
- Type of population:
- occupational
- Subjects:
- - Number of subjects exposed: 2
- Sex: not specified
- Age: not specified - Ethical approval:
- not applicable
- Route of exposure:
- dermal
- Reason of exposure:
- unintentional, occupational
- Exposure assessment:
- not specified
- Details on exposure:
- Two workers were exposed to the chemical while transferring the chemical from a drum to a smaller pail and contaminted. The workers were not wearing personal protective equipments other than latex gloves.
- Examinations:
- Exposed skin areas; face, hands and an arm of one worker and hands of second worker were examined.
- Medical treatment:
- Not specified.
Results and discussion
- Clinical signs:
- No clinical signs noted.
- Results of examinations:
- No symptoms of any skin reactions to the chemical noted.
Any other information on results incl. tables
Two workers were exposed to the chemical (D40) while transferring the chemical from a drum to a smaller pail and contaminted. The workers were not wearing personal protective equipments other than latex gloves. The workers were escorted to the emergency room. The accidental exposure to face, hands and an arm of one worker and to a hands of other worker resulted no injuries from the chemical. No symptoms of any skin reactions to the chemical noted. The workers were discharged after thorough medical investigations.
Applicant's summary and conclusion
- Conclusions:
- No symptoms of any skin reactions to the chemical noted in the exposed workers.
- Executive summary:
The accidental occupational exposure of workers to 2,2',2''-Nitrilotriethanol, propoxylated resulted no signs of any skin reactions (irritation/corrosion or skin sensitisation).
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