Registration Dossier
Registration Dossier
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EC number: 225-464-3 | CAS number: 4861-19-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Additional information:
Urea phosphate is directly dissociated into urea and phosphoric acid.
Urea is naturally present at relatively high concentrations in human skin (up to 1% by weight) and is widely used in skin creams for the treatment of dry and irritant skin conditions without any reports of sensitisation reactions. It is therefore considered to be very unlikely to be a skin sensitiser.
Urea phosphate and phosphoric acid are classified as a skin corrosive substance category 1B according to the CLP Regulation Annex VI, table 3.1 (EC Regulation 1272/2008 on classification, labeling and packaging of substances and mixtures). According to the REACH Regulation, testing for skin sensitization does not need to be conducted as the substance is classified as corrosive to the skin.
Migrated from Short description of key information:
Urea phosphate is classified as a skin corrosive substance category 1B, therefore testing for skin sensitization does not need to be conducted.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No data
Justification for classification or non-classification
Phosphoric acid and thus urea phosphate is classified as skin corrosive, thus a further assessment for skin sensitization is not necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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