Registration Dossier
Registration Dossier
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EC number: 239-898-6 | CAS number: 15793-73-4
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- other: case report
- Adequacy of study:
- supporting study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Case report
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 985
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 987
Materials and methods
- Study type:
- other: Case report
- Endpoint addressed:
- skin sensitisation
- Principles of method if other than guideline:
- no guideline required
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4,4'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-(p-tolyl)-3H-pyrazol-3-one]
- EC Number:
- 239-898-6
- EC Name:
- 4,4'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[2,4-dihydro-5-methyl-2-(p-tolyl)-3H-pyrazol-3-one]
- Cas Number:
- 15793-73-4
- Molecular formula:
- C34H28Cl2N8O2
- IUPAC Name:
- 4,4'-[(3,3'-dichlorobiphenyl-4,4'-diyl)didiazene-2,1-diyl]bis[5-methyl-2-(4-methylphenyl)-2,4-dihydro-3H-pyrazol-3-one]
Constituent 1
Method
- Subjects:
- - Number of subjects exposed: 1
- Sex: female
- Age: 49
- Demographic information: cleaning personal
- Known diseases: sensitisation to rubber - Route of exposure:
- dermal
- Reason of exposure:
- intentional, occupational
- Exposure assessment:
- not specified
Results and discussion
- Clinical signs:
- symptoms: sharply defined glove dermatitis after wearing of PVC gloves
Any other information on results incl. tables
Patch test with glove: weak reaction
Other ingredients: negative
10 control tests with pigment (2% in petrolatum): negative
Applicant's summary and conclusion
- Executive summary:
One case report documents the sensitisation to Irgalite Orange F2G (Pigment Orange 34) after the use of PVC gloves.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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