Registration Dossier
Registration Dossier
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EC number: 939-382-7 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Based on REACH regulation annex IX column 2 (specific rules for adaptation from column 1) the study need not be conducted if the substance has a low potential for bioaccumulation (for instance a log Kow < 3) and/or a low potential to cross biological membranes. Partition coefficient was estimated resulting in a logPow of -3.27
There are no empirical bioaccumulation data available for Direct Black 22 (DBk22), therefore available data on water solubility, molecular weight and cross-sectional diameter have also been considered in order to determine the bioaccumulation potential of DBk22, as well as the physical and chemical properties of the relevant analogues (disulfonated dyes) used in a Canadian screening assessment of dye characterization [1].
DBk22 is a relatively large molecule and is expected to have a low bioaccumulation potential due to its physical and chemical properties and based on the comparison with analogues.
REFERENCE:
[1] Screening Assessment for the Challenge, 2,7-Naphthalenedisulfonic acid, 4-amino-3-[[4'-[(2,4-diaminophenyl) azo][1,1'-biphenyl]-4-yl]azo]-5 - hydroxy -6- (phenylazo) -, disodium salt (Direct Black 38) Chemical Abstracts Service Registry Number 1937-37-7. Environment Canada Health Canada, November 2009. Available on: http: //www. ec. gc. ca/ese-ees/default. asp?lang=En&n=7C287737-1#a8
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