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EC number: 202-808-0 | CAS number: 99-99-0
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- not specified
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Temp.:
- 53.7 °C
- Vapour pressure:
- 1.3 hPa
- Temp.:
- 100 °C
- Vapour pressure:
- 13.3 hPa
- Executive summary:
Hoechst MSDS, 1993
The vapour pressure of 4-nitrotoluene is reported as 1.3 hPa at 53.7 °C and as 13.3 hPa at 100 °C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original reference not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Temp.:
- 30 °C
- Vapour pressure:
- 0.27 hPa
- Temp.:
- 50 °C
- Vapour pressure:
- 1 hPa
- Executive summary:
Auergesellschaft, 1988
The vapour pressure of 4-nitrotoluene is reported as 0.27 hPa at 30 °C and as 1 hPa at 50 °C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Adopted according to OECD SIDS (public available peer reviewed source)
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- no data
- GLP compliance:
- not specified
- Temp.:
- 20 °C
- Vapour pressure:
- 0.13 hPa
- Executive summary:
Auergesellschaft, 1988
The vapour pressure of 4-nitrotoluene is reported as 0.13 hPa at 20 °C.
- Endpoint:
- vapour pressure
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Temp.:
- 25 °C
- Vapour pressure:
- 0.164 mm Hg
- Remarks on result:
- other: extrapolated
- Executive summary:
HSDB, 2009
The vapour pressure of 4-nitrotoluene is reported as 0.164 mm Hg at 25 °C (extrapolated value).
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): p-Nitrotoluene
- Analytical purity: not specified - Temp.:
- 55 °C
- Vapour pressure:
- 1.3 hPa
- Executive summary:
Hommel, 1997
The vapour pressure of 4-nitrotoluene is reported as 1.3 hPa at 55 °C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): 4-Nitrotoluol
- Analytical purity: not specified - Temp.:
- 20 °C
- Vapour pressure:
- 0.13 hPa
- Executive summary:
Roempp Online, 2009
The vapour pressure of 4-nitrotoluene is reported as 0.13 hPa at 20 °C.
Referenceopen allclose all
Description of key information
The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.
The vapour pressure of 4-nitrotoluene was determined in a series of experimental studies. The values are in a similar range depending on the temperature.
Roempp Online, 2009: The vapour pressure of 4-nitrotoluene is reported as 0.13 hPa at 20 °C.
Hommel, 1997: The vapour pressure of 4-nitrotoluene is reported as 1.3 hPa at 55 °C.
HSDB, 2009: The vapour pressure of 4-nitrotoluene is reported as 0.164 mm Hg at 25 °C (extrapolated value).
Auergesellschaft, 1988: The vapour pressure of 4-nitrotoluene is reported as 0.13 hPa at 20 °C, 0.27 hPa at 30 °C and as 1 hPa at 50 °C.
Hoechst MSDS, 1993: The vapour pressure of 4-nitrotoluene is reported as 1.3 hPa at 53.7 °C and as 13.3 hPa at 100 °C.
Beilstein, 2002: The vapour pressure of 4-nitrotoluene is reported as 0.055 hPa at 25 °C.
The value reported by Roempp was chosen as key value for chemical safety assessment.
Key value for chemical safety assessment
- Vapour pressure:
- 0.13 hPa
- at the temperature of:
- 20 °C
Additional information
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