Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 250-178-0 | CAS number: 30399-84-9
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only secondary literature
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- 4 Final Report on the Safety Assessment of Isostearic Acid
- Author:
- Cosmetic Ingredient Review (CIR)
- Year:
- 1 983
- Bibliographic source:
- Journal of the American College of Toxicology 2(7):61-74
Materials and methods
- Type of study / information:
- Clinical Assessment of Safety: Primary Skin Irritation
- Endpoint addressed:
- skin irritation / corrosion
- Principles of method if other than guideline:
- 24 h occlusive patch test
- GLP compliance:
- no
Test material
- Reference substance name:
- Isooctadecanoic acid
- EC Number:
- 250-178-0
- EC Name:
- Isooctadecanoic acid
- Cas Number:
- 30399-84-9
- Molecular formula:
- not applicable (UVCB substance)
- IUPAC Name:
- 2-methylheptadecanoic acid
- Details on test material:
- - Name of test material (as cited in study report): Isostearic Acid
- Analytical purity: no data
Constituent 1
Method
- Details on study design:
- A 24 h occlusive patch test procedure was used to evaluate the primary skin irritation caused by undiluted lsostearic Acid.
- Exposure assessment:
- not specified
Results and discussion
- Results:
- The undiluted ingredient tested “negative” in the single insult patch test.
Applicant's summary and conclusion
- Conclusions:
- not irritating
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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