Registration Dossier
Registration Dossier
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EC number: 244-742-5 | CAS number: 22036-77-7
Endpoint summary
Administrative data
Description of key information
An acute oral LD50 value of >10000 ml/kg was reported in a study conducted according to an appropriate protocol equivalent to current guideline and in compliance with GLP. The LD50 in terms of active acid was estimated to equal to >3250 mg/kg (Safepharm 1982).
No data was available for acute inhalation.
Key value for chemical safety assessment
Additional information
The most recent and reliable studies were selected as key. However, reliable supporting studies were also available for acute oral and dermal toxicity endpoints, which supported the key findings.
The LD50 in terms of active acid content for the key studies is estimated to be 3250 mg/kg, which equals to 4230 mg/kg active salt at pH 7.
No data was available for the acute inhalation endpoint. Since reliable data were available for the acute oral and dermal toxicity endpoints, inhalation data is waived.
The acute toxicity of EDTMP sodium salt is therefore concluded to be low.
Justification for classification or non-classification
Based on the available data, no classification is proposed for EDTMP sodium salt (CAS 22036-77-7) in accordance with current guideline (EC 1272/2008).
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