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Diss Factsheets

Administrative data

Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
Not reported
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The study was conducted according to OECD Guideline 112
Justification for data waiving:
other:
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1985

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
Deviations:
not specified
Principles of method if other than guideline:
Not applicable
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(carboxymethyl)-N-(phosphonomethyl)glycine
EC Number:
227-824-5
EC Name:
N-(carboxymethyl)-N-(phosphonomethyl)glycine
Cas Number:
5994-61-6
Molecular formula:
C5H10NO7P
IUPAC Name:
2-[(carboxymethyl)(phosphonomethyl)amino]acetic acid
Details on test material:
- Name of test material (as cited in study report): N-(phosphonomethyl) iminodiacetic acid (glyphosate intermediate)

Results and discussion

Dissociating properties:
yes
Dissociation constantopen allclose all
No.:
#1
pKa:
2
Temp.:
20 °C
Remarks on result:
other: (in 0.1N KCL at 20°C (293°K))
No.:
#2
pKa:
2.25
Temp.:
20 °C
Remarks on result:
other: (in 0.1N KCL at 20°C (293°K))
No.:
#3
pKa:
5.57
Temp.:
20 °C
Remarks on result:
other: (in 0.1N KCL at 20°C (293°K))
No.:
#4
pKa:
10.76
Temp.:
20 °C
Remarks on result:
other: (in 0.1N KCL at 20°C (293°K))

Any other information on results incl. tables

None

Applicant's summary and conclusion

Conclusions:
Under the test conditions, the dissociation constant of the four test material samples (1, 2, 3 and 4), denoted as pk1, pk2, pk3 and pk4 were 2.0, 2.25, 5.57 and 10.76 respectively in 0.1N KCL at 20 °C.
Executive summary:

Under the test conditions, the dissociation constant of the four test material samples (1, 2, 3 and 4), denoted as pk1, pk2, pk3 and pk4 was 2.0, 2.25, 5.57 and 10.76 respectively in 0.1N KCL at 20 °C.