Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1982
Reference Type:
secondary source
Title:
SIDS Category of Alkyl sulfates, Alkane sulfonates and Alpha-olefin sulfonates
Author:
OECD
Year:
2007
Bibliographic source:
UNEP Publications

Materials and methods

Principles of method if other than guideline:
Method: other
GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Reference substance name:
85681-68-1 (purity 55%)
IUPAC Name:
85681-68-1 (purity 55%)
Details on test material:
- Name of test materail (as cited in study report): trade name
- Physical state: No data
- Analytical purity: 55% a.i.
- Lot / batch No.: No data
- Storage conditions of test material: No data

Test animals

Species:
rat
Strain:
Wistar
Sex:
male

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
water
Doses:
3160, 3980, 5010, 5320, 5630, 6250 and 7000 mg/kg bw
No. of animals per sex per dose:
10
Control animals:
no

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
5 500 mg/kg bw
Based on:
act. ingr.

Any other information on results incl. tables

LD50 range: 5000 - 6050 mg/kg

MORTALITY:
-Time of death: 2 hrs - 2 days
-Number of deaths at each dose: 0/10, 1/10, 3/10, 5/10, 6/10, 7/10 or 10/10

CLINICAL SIGNS: diarrhoea, piloerection, increased breathing

NECROPSY FINDINGS: no adverse effects at macroscopic examination

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU