Registration Dossier
Registration Dossier
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EC number: 615-309-1 | CAS number: 7159-96-8
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1.3.-1.5.1976
- Reliability:
- 3 (not reliable)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- Methyl (3-hydroxyphenyl)-carbamate
- EC Number:
- 237-196-4
- EC Name:
- Methyl (3-hydroxyphenyl)-carbamate
- Cas Number:
- 13683-89-1
- IUPAC Name:
- methyl (3-hydroxyphenyl)carbamate
- Reference substance name:
- methyl-N-(3-hydroxyphenyl)-carbamate
- IUPAC Name:
- methyl-N-(3-hydroxyphenyl)-carbamate
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- male
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- olive oil
- Details on oral exposure:
- 10% suspense of the substance in olive oil.
- Doses:
- 1585 mg/kg bw
1995 mg/kg bw
2512 mg/kg bw
3163 mg/kg bw - No. of animals per sex per dose:
- 10
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 2 385 mg/kg bw
- Based on:
- test mat.
- Mortality:
- 1 animal of 10 by dose 1585 mg/kg bw
4 animals of 10 by dose 1995 mg/kg bw
7 animals of 10 by dose 2512 mg/kg bw
9 animals of 10 by dose 3163 mg/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information LD50 > 2000 mg/kg bw Criteria used for interpretation of results: EU
- Conclusions:
- The substance is slighly toxic by oral route but not classified according to CLP and DSD criteria.
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