Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 500-036-1 | CAS number: 25214-70-4
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
A full discussion on the justification on read-across of data for the 4,4´-isomer of MDA for oligomeric MDA in the scope of REACH is presented in section 7.6 of this CSR.
In the TNO study toxic effects of 4,4'-MDA to terrestrial plants Avena sativa and Lactuca sativa were observed (TNO, 1992). Valid results from the short-term toxicity tests with plants were obtained. Results from long-term tests are not available. Therefore the lowest acute toxicity test result (ie EC50 = 128 mg MDA/kg soil (d.w.)) may be considered, together with an assessment factor of 1000, to derive a PNEC value.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
