Registration Dossier
Registration Dossier
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EC number: 424-250-9 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 1997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Yellow MGi 1301
- IUPAC Name:
- Yellow MGi 1301
- Test material form:
- solid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Nominal and measured concentrations:
- 200 mg/l (nominal)
- Details on test conditions:
- A limit test was performed to demonstrate that the test substance has no toxic effect on the test animals up to the concentration of nominal 200 mg test substance/I. Thus the only concentration tested was nominal 200 mg test substance/l and a control.
The analytically determined test substance concentrations in the freshly prepared test media varied between 101 and 102 % of the nominal value. During the renewal period of 24 hours a decrease of test substance concentration to 54 % of the nominal value was measured, if the quantification is based on the main compound. If the quantification is based on the sum of main compound and main degradation product 104 % of the nominal value were found.
Since the analytically determined test substance concentrations at the start of the test were in good agreement with the nominal test concentration, the reported biological results are related to the nominal test substance concentration.
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 200 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Applicant's summary and conclusion
- Conclusions:
- NOEC = 200 mg/l
EC50 (48 h) > 200 mg/l
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