Registration Dossier
Registration Dossier
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EC number: 202-849-4 | CAS number: 100-41-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 3 500 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Dose descriptor:
- LC50
- Value:
- 17 400 mg/m³
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 17 800 mg/kg bw
Additional information
The experimental data set on acute toxicity of ethylbenzene include studies by inhalation, oral and dermal exposure performed in rodents. These data support classification of ethylbenzene as Category 4, Acute inhalation substance.
Ethylbenzene has harmonized classification in the EU and it is classified as Acute toxicity - inhalation: Acute Tox. 4; H332: Harmful if inhaled, according to the GHS criteria of Regulation (EC) No 1272/2008 (Annex VI, table 3.1) and Acute toxicity: Xn; R20 Harmful; Harmful by inhalation, according to the DSD/DPD criteria of Annex I of Directive 67/548/EEC and as reported in Regulation (EC) No 1272/2008 (Annex VI, table 3.2).
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
