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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Test conducted according to EU Method C. 1 and compliant with GLP.

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1997

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
Deviations:
not specified
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide
EC Number:
423-340-5
EC Name:
Phenyl bis(2,4,6-trimethylbenzoyl)-phosphine oxide
Cas Number:
162881-26-7
Molecular formula:
C26H27O3P
IUPAC Name:
[phenyl(2,4,6-trimethylbenzoyl)phosphoryl](2,4,6-trimethylphenyl)methanone
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Test solutions

Details on test solutions:
Identity and concentration of auxiliary solvent for dispersal: None

Test organisms

Test organisms (species):
other: Zebra Fish Brachydanio rerio

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Test conditions

Hardness:
250 mg CaCO3/L

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
> 0.09 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
> 0.09 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
> 0.09 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 0.09 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC100
Effect conc.:
> 0.09 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
> 0.09 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Details on results:
In the control and all test concentrations, all fish survived until the end of the test and no signs of intoxication were observed. The substance was tested at levels above the water solubility and the solubility of the substance in the test water was determined to be 0.0008 mg/L. Therefore, the test substance can be classified as non-toxic to fish up to the limit of its solubility.

Applicant's summary and conclusion

Conclusions:
The test substance can be classified as non-toxic to fish up to the limit of its solubility.