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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
publication
Title:
No information
Year:
1982
Bibliographic source:
Gigiena i Sanitariya HYSAAV Vol.47(3), Pg. 88, 1982 (ChamIDplus Lite data base)

Materials and methods

Test guideline
Guideline:
other: not known
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-chloro-α,α,α-trifluoro-3-nitrotoluene
EC Number:
204-451-6
EC Name:
4-chloro-α,α,α-trifluoro-3-nitrotoluene
Cas Number:
121-17-5
Molecular formula:
C7H3ClF3NO2
IUPAC Name:
1-chloro-2-nitro-4-(trifluoromethyl)benzene

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
1 075 mg/kg bw

Any other information on results incl. tables

Behavioral effects: somnolence (general depressed activity), tremor and ataxia

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The DL50 is < 2000 mg/l therefore the substance is classifed as harmful for ingestion.