Registration Dossier
Registration Dossier
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EC number: 226-134-1 | CAS number: 5292-45-5
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
Experimental date related to skin or respiratory sensitizing properties of dimethy 2-nitroterephthalate are not available. QSAR-Analysis using the OECD QSAR Toolbox revealed a negative prediction for skin sensitizing properties with a confidence level of 83.3%. Additionally methyl hydrogen 2-nitroterephthalate a substance of similar chemical structure with similar PC-data (water solubility, Log Pow) was found to be not a skin sensitizer when tested in the LLNA. Based on these data dimethyl 2-nitroterephthalate was considered to be not a skin sensitizer.
Migrated from Short description of key information:
OECD QSAR toolbox: negativ
Read across substance of similar chemical structure and similar PC-data: negative
Conclusion for dimethyl 2-nitroterephthalate: negative
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
