Registration Dossier
Registration Dossier
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EC number: 220-040-4 | CAS number: 2612-57-9
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of 2,4-dichloroaniline, being the hydrolysis product of 2,4-dichlorophenyl isocyanate, towards aquatic algae is
characterized by an EC50 (72 h) of > 9.9 mg/L and a NOEC (72 h) of 2.0 mg/L (MITI-online, 1995).
Key value for chemical safety assessment
Additional information
Isocyanates are known to rapidly hydrolyse under the formation of the corresponding amine. Thus, it is not possible to obtain a stable concentration of 2,4-dichlorophenyl isocyanate over the whole test duration due to its rapid hydrolysis and observed effects would be rather caused by the transformation product (2,4-dichloro aniline) than by the original substance itself. Concluding, results obtained through the testing of 2,4-dichloro aniline can be used to assess the risk of 2,4-dichlorophenyl isocyanate towards aquatic organisms as well.
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