Registration Dossier
Registration Dossier
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EC number: 247-415-5 | CAS number: 26021-57-8
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Data waiving:
- exposure considerations
- Justification for data waiving:
- the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size
- Justification for type of information:
- JUSTIFICATION FOR DATA WAIVING
Exposure to Hydroxybenzomorpholine via the inhalation route is unlikely. Indeed, The relatively high melting temperature (113.2 °C) and the low vapour pressure (1.66 x 10 -3 Pa at 20°C), indicate that it is not likely that Hydroxybenzomorpholine vapours will reach the nasopharyngeal region or subsequently the tracheobronchial or pulmonary region. In addition, the relatively high average median particle size (143μm) prevents particles to be inhaled, as these have an aerodynamic diameter higher than 100 μm. Thus, Hydroxybenzomorpholine has a low potential to be inhaled.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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