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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
96 hours
Reliability:
2 (reliable with restrictions)
Justification for type of information:
Data on the starting reagent (alkylamine) provides a useful indicator of overal hazard and helps build a picture for wider read-across between the class of substances.
This demonstrates that fish are not the most sensitive organism to this type of substance. Further testing on vertebrates cannot be justified.
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
not specified
Analytical monitoring:
yes
Vehicle:
yes
Details on test solutions:
Surfactant used to aid dispersion
Test organisms (species):
other: Brachydanio rerio
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
ca. 0.71 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Validity criteria fulfilled:
not specified
Conclusions:
Although clearly toxic to fish, it is noted that Daphnia were the more sensitive organism.
Data on the starting reagent (alkylamine) provides a useful indicator of overal hazard and helps build a picture for wider read-across between the class of substances.
This demonstrates that fish are not the most sensitive organism to this type of substance. Further testing on vertebrates cannot be justified.

Description of key information

The starting alkylamine has been used for this assessment and although clearly toxic to fish, it is noted that Daphnia were the more sensitive organism.

For this reason, further testing on vertebrates is not justified and classification is based on Daphnia effects.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
0.71 mg/L

Additional information