Registration Dossier
Registration Dossier
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EC number: 500-429-8 | CAS number: 159034-96-5
Endpoint summary
Administrative data
Link to relevant study record(s)
- Endpoint:
- basic toxicokinetics, other
- Type of information:
- other: assessment
- Adequacy of study:
- key study
Reference
Description of key information
No toxicokinetics studies are available for absorption of assessed substance. Based on its physico-chemcial properties and available toxicological studies, assessed substance is demonstrated to be absorbed following oral administration and a default value of 100% may be assumed. Absorption via the dermal route is considered to be a default value of 100% skin absorption in case ofestimated Log Pow values is the range [-1, 4].The inhalation absorption is relevant via exposure to dust due to substance’s particle size.
No experimental data on the distribution properties/metabolism/ excretion of assessed substance is available.
Accumulation in tat tissue is expected to occur due to lipophilic substance (log P >0). The assessed substance is considered to be excreted in the faeces due to low water solubility and the high molecular mass.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
