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Diss Factsheets

Administrative data

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09 February 2018 - 20 March 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
GLP compliance:
no
Type of method:
other: gas comparison stereopycnometer

Test material

Constituent 1
Chemical structure
Reference substance name:
Disodium L-cystinate
EC Number:
265-025-3
EC Name:
Disodium L-cystinate
Cas Number:
64704-23-0
Molecular formula:
C6H10N2Na2O4S2.H2O
IUPAC Name:
disodium (2R)-2-amino-3-{[(2R)-2-amino-2-carboxyethyl]disulfanyl}propanoate
Test material form:
solid: particulate/powder

Results and discussion

Density
Key result
Type:
relative density
Density:
ca. 1.63
Temp.:
20 °C

Any other information on results incl. tables

 Interpretation: The density (ρ) of a substance is the quotient of its mass and its volume and is expressed in SI units of kg/m3. The relative density ( ) is the ratio between the mass of a volume of a substance to be examined, determined at 20°C, and the mass of the same volume of water, determined at 4°C ( = 1000 kg/m3). The relative density has no dimension.

 

Density ρ = m/V [g/cm3]

Where:

m: mass of the test item [g]

V: volume of the test item [cm3]

 

Results: The results of the tests on the determination of the density of the test item are given in the table below. The individual measurements were obtained with an accuracy of < 0.02 g/cm3. According to the guideline, the density of the test item is given as the mean value.        

Density of the Test Item

 

Test 1

Test 2

Mean

Density [g/cm3]

1.626

1.624

1.63

Applicant's summary and conclusion

Conclusions:
A gas comparison stereopycnometer was used for the determination of the density and relative density of Disodium L-cystinate. The density of the test item at 20ºC was 1.63 g/cm3 (1.63 x 103 kg/m3). The relative density was 1.63.
Executive summary:

A gas comparison stereopycnometer was used for the determination of the density and relative density of Disodium L-cystinate. The density of the test item at 20ºC was 1.63 g/cm3(1.63 x 103kg/m3). The relative density was 1.63.