4-methylbenzothiazol-2-ylamine

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

conducted to determine the boiling point, but melting point result included, too

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

other: OECD Guideline 103 (Boiling Point)

Deviations:

no

Qualifier:

according to guideline

Guideline:

other: EU Method A.2 (Boiling Temperature)

Deviations:

no

Principles of method if other than guideline:

Melting point has been determined in boiling point determination, too

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

ca. 138 °C

Atm. press.:

101.1 kPa

Decomposition:

yes

Decomp. temp.:

250 °C

Remarks on result:

other: partial boiling with decomposition at 250 °C; two measurements have been made

Conclusions:

The study was conducted under GLP according to OECD guideline 103 on the registered substance itself. The method is to be considered scientifically reasonable with no deficiencies in documentation or any deviations although the guideline is designed for the determination of the boiling point and therefore reliability of Klimisch 2 has been assigned. The substance partially melts at ca. 138 °C.

Executive summary:

Melting point has been determined to be at 138°C (101.1 kPa) by differential scanning calorimetry, designed to be compatible with EU method A.2 B and OECD Guideline 103 (GLP).

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Report date:

2017

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Test material

Test material information

1

Reference substance name:

4-methylbenzothiazol-2-ylamine

EC Number:

216-028-3

EC Name:

4-methylbenzothiazol-2-ylamine

Cas Number:

1477-42-5

Molecular formula:

C8H8N2S

IUPAC Name:

4-methyl-1,3-benzothiazol-2-amine

Test material form:

solid: particulate/powder

Results and discussion

Boiling point

Key result

Boiling pt.:

250 °C

Atm. press.:

101.1 kPa

Decomposition:

yes

Decomp. temp.:

250 °C

Remarks on result:

other: Partial boiling with decomposition

Applicant's summary and conclusion

Conclusions:

The study was conducted under GLP according to OECD guideline 103 on the registered substance itself. The method is to be considered scientifically reasonable with no deficiencies in documentation or any deviations and therefore reliability of Klimisch 1 has been assigned. The substance partially boils with decomposition from approx. 250 °C.

Executive summary:

Partial boil with decomposition from approximately 250 °C (523 K) at 101.1 kPa by differential scanning calorimetry, designed to be compatible with EU method A.2 B and OECD Guideline 103 (GLP).