Registration Dossier
Registration Dossier
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EC number: 200-782-5 | CAS number: 72-48-0
Toxicity to birds
Administrative data
- Endpoint:
- short-term toxicity to birds: acute oral toxicity test (LD50-only)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- Not specified in publication
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- The acute oral toxicity, repellency and hazard potential of 998 chemicals to one or more species of wild and domestic birds
- Author:
- Schafer EW, Bowles WA, Hulbut J
- Year:
- 1 983
- Bibliographic source:
- Arch. Environ. Contam. Toxicol.
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Wild-trapped birds were dosed by gavage with solutions or suspensions of the test material
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,2-dihydroxyanthraquinone
- EC Number:
- 200-782-5
- EC Name:
- 1,2-dihydroxyanthraquinone
- Cas Number:
- 72-48-0
- Molecular formula:
- C14H8O4
- IUPAC Name:
- 1,2-dihydroxy-9,10-dihydroanthracene-9,10-dione
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- Test material info not available
- Dose method:
- gavage
- Analytical monitoring:
- no
- Vehicle:
- yes
- Remarks:
- propylene glycol
Test organisms
- Test organisms (species):
- other: wild-trapped birds
- Details on test organisms:
- - Preconditioned to captivity: 2 to 6h
Study design
- Limit test:
- no
Results and discussion
Effect levels
- Dose descriptor:
- LC50
- Effect level:
- 316 mg/kg bw
- Conc. / dose based on:
- test mat.
- Basis for effect:
- mortality
Applicant's summary and conclusion
- Validity criteria fulfilled:
- no
- Conclusions:
- The effect of the test item on birds was assessed. The reported LD50 is 316 mg/kg body weight.
- Executive summary:
The acute oral toxicity of 1,2 -dihydroxyanthraquinone was assessed. Wild-trapped birds were pre- conditioned to captivity for 2 to 6 weeks and were dosed by gavage with solutions or suspension of the test chemical in propylene glycol. The reported LD50 is 316 mg/kg body weight.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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