Registration Dossier
Registration Dossier
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EC number: 229-765-0 | CAS number: 6713-03-7
Endpoint summary
Administrative data
Description of key information
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation.
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation, other
- Type of information:
- other: expert assessment
- Adequacy of study:
- key study
- Study period:
- August 11, 2017
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- Principles of method if other than guideline:
- Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- GLP compliance:
- no
- Type of study:
- other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
- Key result
- Parameter:
- other: skin sensitisation
- Remarks on result:
- other: 1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- 1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation.
- Executive summary:
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation.
Reference
see attached report
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
Justification for classification or non-classification
An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol did not meet the criteria for classification according to Regulation (EC) No.1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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