Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
publication
Title:
Glycidyloxy Compounds Used in Epoxy Resin Systems: A Toxicology Review
Author:
Gardiner Thomas H & al
Year:
1992
Bibliographic source:
REGULATORY TOXICOLOGY AND PHARMACOLOGY 15, S1 -S77 ( 1992)

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Oxirane, mono[(C8-10-alkyloxy)methyl] derivs.
EC Number:
271-845-2
EC Name:
Oxirane, mono[(C8-10-alkyloxy)methyl] derivs.
Cas Number:
68609-96-1
Molecular formula:
C11H22O2, C12H24O2, C13H26O2
IUPAC Name:
2-[(decyloxy)methyl]oxirane; 2-[(octyloxy)methyl]oxirane
Test material form:
liquid

Test animals

Species:
rat

Administration / exposure

Route of administration:
inhalation
Duration of exposure:
4 h
Concentrations:
0.05 to 1.5 mg/L

Results and discussion

Effect levels
Dose descriptor:
LC50
Effect level:
> 1.5 mg/L air (nominal)
Exp. duration:
4 h

Applicant's summary and conclusion