Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Recommendation from Scientific Expert Group on Occupational Exposure Limits
Year:
1991
Bibliographic source:
Recommendation from Scientific Expert Group on Occupational Exposure Limits for Heptan-2-one, 1991

Materials and methods

Principles of method if other than guideline:
Method not avaiilable
GLP compliance:
not specified
Test type:
other: not available

Test material

Constituent 1
Chemical structure
Reference substance name:
Heptan-2-one
EC Number:
203-767-1
EC Name:
Heptan-2-one
Cas Number:
110-43-0
Molecular formula:
C7H14O
IUPAC Name:
heptan-2-one

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Duration of exposure:
4 h

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
other: LC10
Effect level:
4 000 ppm
Exp. duration:
4 h
Mortality:
death of all animals tested

Applicant's summary and conclusion

Interpretation of results:
Category 4 based on GHS criteria
Conclusions:
The substance is classified as harmful if inhaled (CLP Regulation - category 4)