Registration Dossier
Registration Dossier
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EC number: 213-944-5 | CAS number: 1068-27-5
Endpoint summary
Administrative data
Description of key information
In a closed bottle test according to OECD guideline 301, no biodegradation was observed.
Additional information
A ready biodegradability test with the test item
in mineral oil was performed which allows the biodegradability to be
measured in an aerobic aqueous medium. The ready biodegradability was
determined in the Closed Bottle test performed according to OECD
guideline 301 and EU method C.6. The test was prolonged because the pass
level was not reached at day 28.
Slight inhibition of the endogenous respiration of the inoculum by the
test substance and mineral oil was detected. Therefore, inhibition of
the biodegradation due to the "high" initial concentrations may occur.
The test item in solvent was biodegraded 4 % at day 28 in the Closed
Bottle test. In the prolonged Closed Bottle test this compound was
biodegraded 0 % at day 140. Under the test conditions chosen, no
biodegradation was observed.
The validity of the test is demonstrated by
an endogenous respiration of 1.6 mg/L at day 28. Furthermore, the
differences of the replicate values at day 28 were less than 20 %. The
biodegradation percentage of the reference compound, sodium acetate, at
day 14 was 83. Finally, the validity of the test is shown by oxygen
concentrations > 0.5 mg/L in all bottles during the test period.
The test substance should be classified as not biodegradable. Lack of
biodegradation does not mean that the test item in mineral oil is
recalcitrant in nature. The stringency of the test procedures could
account for the recalcitrance in the Closed Bottle test.
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