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REACH

Octane-1-thiol

EC number: 203-918-1 | CAS number: 111-88-6

Life Cycle description
Uses advised against

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The 96 hr Oryzias latipes LC50 is 0.326 mg /L. This is supported by read across from dodecane-1-thiol. The 96 hour Onchorhynchus mykiss LC50 is >100 mg a.i./L and the NOEC is 100 mg a.i./L.

Key value for chemical safety assessment

Fresh water fish

Effect concentration:: 0.326 mg/L

Additional information

The study by MOE (2004) is only available as a summary and so it has not been fully evaluated. This study is used as a critical study for the SIDS endpoint and is used in the IUCLID Data Set for Octane-1-thiol (2004). The study has been given a Klimisch score 1 - reliable without restrictions (Klimisch et al, 1997) in the IUCLID Data Set and is here considered as Klimisch 1 untill the reference is available and being sponsored by MOE one can consider the study as relevant.

This is supported by read across from dodecane-1 -thiol. Collins (1998) is a GLP-compliant, 96 hour study on Oncorhynchus mykiss following TSCA guidelines 797.1400. The study is considered reliable and suitable for use for this endpoint.

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