Registration Dossier
Registration Dossier
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EC number: 206-496-7 | CAS number: 350-03-8
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- other: publication
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only short abstract available - Only secondary literature
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of 3-acetyl pyridine in tuberculous and cord factor treated mice
- Author:
- Windman I.
- Year:
- 1 969
- Bibliographic source:
- Life Sciences Volume 8, Issue 1, 1 January 1969, Pages 73–77
Materials and methods
- Principles of method if other than guideline:
- No information is given on test method
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methyl 3-pyridyl ketone
- EC Number:
- 206-496-7
- EC Name:
- Methyl 3-pyridyl ketone
- Cas Number:
- 350-03-8
- Molecular formula:
- C7H7NO
- IUPAC Name:
- 1-(pyridin-3-yl)ethan-1-one
- Details on test material:
- - Name of test material (as cited in study report) : 3-Acetyl pyridine
Constituent 1
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No details available
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- not specified
- Details on exposure:
- No details available
- Doses:
- No details available
- No. of animals per sex per dose:
- No details available
- Control animals:
- not specified
- Details on study design:
- No details available
- Statistics:
- No details available
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 375 mg/kg bw
- Based on:
- not specified
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 195 mg/kg bw
- Based on:
- not specified
- Mortality:
- No details available
- Clinical signs:
- No details available
- Body weight:
- No details available
- Gross pathology:
- No details available
Applicant's summary and conclusion
- Conclusions:
- The following LD50-values (intraperitoneal) in the mouse were reported : 375 mg/kg and 195 mg/kg (Windman,1969).
- Executive summary:
The following LD50-values (intraperitoneal) in the mouse were reported : 375 mg/kg and 195 mg/kg (Windman,1969).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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