Registration Dossier
Registration Dossier
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EC number: 403-500-0 | CAS number: 159120-95-3 CYRACURE (R) PHOTOINITIATOR UVI-6974; CYRACURE PHOTOINITIATOR UVI-6976
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- no data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study was performed according to EC guidelines and according to GLP principles. Data submitted previously than 12 years; provided by ECHA on registrant's request.
Data source
Reference
- Reference Type:
- other: information from migrated NONS file provided by ECHA
- Title:
- Unnamed
- Year:
- 1 989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.3 (Algal Inhibition test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate
- EC Number:
- 403-500-0
- EC Name:
- A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate
- Cas Number:
- 159120-95-3
- Molecular formula:
- C24H19S2.F6Sb and C36H28S3.2F6Sb
- IUPAC Name:
- (4-{[4-(diphenylsulfaniumyl)phenyl]sulfanyl}phenyl)diphenylsulfanium; diphenyl[4-(phenylsulfanyl)phenyl]sulfanium; tris(hexafluorostibanuide)
- Details on test material:
- no infirmation available
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- no data
Test solutions
- Vehicle:
- no
- Details on test solutions:
- no data
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- no data
Study design
- Test type:
- not specified
- Water media type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 72 h
- Post exposure observation period:
- no data
Test conditions
- Hardness:
- 24 mg CaCO3/l
- Test temperature:
- no data
- pH:
- no data
- Dissolved oxygen:
- no data
- Salinity:
- no data
- Nominal and measured concentrations:
- see below
- Details on test conditions:
- no data
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.023 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.044 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 0.007 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Details on results:
- Analysis of samples take at the end of the test showed that the actual exposure concentrations decreased by more than 20% during the test period. Nominal 0.45 and 1.0 mg/l decreased from 50% at the start of the test to 23 and 26% nominal respectively after 72 hours. The nominal concentration of 0.25 mg/l had decreased to below the detection limit (0.0065 mg/l).
Analysis of the sample taken of the highest concentration without algae showed that the decrease of the test concentrations was not due to the presence of algae.
The nominal/actual values of the concentrations given before are:
EbC50=0.10 / 0.023 mg/l
ErC50 = 0.16 / 0.44 mg/l
NOECb= 0.04 / 0.007 mg/l
A recovery of cell growth was observed during the last 24 hours of exposure, indicated by increased growth rates at the higher test concentrations. This was probably related with the recorded decrease of the actual concentrations during the 72-hour test period. - Results with reference substance (positive control):
- no data
- Reported statistics and error estimates:
- no data
Any other information on results incl. tables
none
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The NOEC (biomass) of the test substance in the algae growth inhibition test was 0.04 / 0.007 mg/l (nominal/actual conc.).
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