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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Peer reviewed data. No more information available.

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2008

Materials and methods

GLP compliance:
not specified
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
Octadecyl methacrylate
EC Number:
251-013-5
EC Name:
Octadecyl methacrylate
Cas Number:
32360-05-7
Molecular formula:
C22H42O2
IUPAC Name:
octadecyl methacrylate

Results and discussion

Test results
Genotoxicity:
negative

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
negative

Using a valid scientific method, Octadecyl methacrylate was negative for genotoxicity in the Salmonella typhimurium reverse mutation assay.
Executive summary:

Using a valid scientific method, Octadecyl methacrylate was negative for genotoxicity in the Salmonella typhimurium reverse mutation assay.